Noninvasive tumor hypoxia measurement using magnetic resonance imaging in murine U87 glioma xenografts and in patients with glioblastoma.
Authors
Linnik, I VScott, M L J
Holliday, K F
Woodhouse, N l
Waterton, J C
O'Connor, James P B
Barjat, H
Liess, C
Ulloa, J
Young, H
Dive, Caroline
Hodgkinson, Cassandra L
Ward, Timothy H
Roberts, Darren L
Mills, S J
Thompson, G
Buonaccorsi, G A
Cheung, S
Jackson, A
Naish, J H
Parker, G J M
Affiliation
Centre for Imaging Sciences, The University of Manchester, Manchester, UKIssue Date
2014-05
Metadata
Show full item recordAbstract
There is a clinical need for noninvasive, nonionizing imaging biomarkers of tumor hypoxia and oxygenation. We evaluated the relationship of T1 -weighted oxygen-enhanced magnetic resonance imaging (OE-MRI) measurements to histopathology measurements of tumor hypoxia in a murine glioma xenograft and demonstrated technique translation in human glioblastoma multiforme.Citation
Noninvasive tumor hypoxia measurement using magnetic resonance imaging in murine U87 glioma xenografts and in patients with glioblastoma. 2014, 71 (5):1854-62 Magn Reson MedJournal
Magnetic Resonance in MedicineDOI
10.1002/mrm.24826PubMed ID
23798369Type
ArticleLanguage
enISSN
1522-2594ae974a485f413a2113503eed53cd6c53
10.1002/mrm.24826
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