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    Phase II trial of Cetuximab and conformal radiotherapy only in locally advanced pancreatic cancer with concurrent tissue sampling feasibility study.

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    Authors
    Rembielak, Agata
    Jain, Pooja
    Jackson, Andrew
    Green, Matthew M L
    Santorelli, Gillian R
    Whitfield, Gillian A
    Crellin, A
    Garcia-Alonso, A
    Radhakrishna, G
    Cullen, James N
    Taylor, Benjamin
    Swindell, Ric
    West, Catharine M L
    Valle, Juan W
    Saleem, Azeem
    Price, Patricia M
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    Affiliation
    Academic Department of Radiation Oncology, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, United Kingdom
    Issue Date
    2014-02
    
    Metadata
    Show full item record
    Abstract
    Preclinical data have indicated the anti-epidermal growth factor receptor (EGFR) agent cetuximab (Erbitux) as a radiosensitizer in pancreatic cancer, but this has not been specifically addressed in a clinical study. We report the results of an original study initiated in 2007, where cetuximab was tested with radiotherapy (RT) alone in locally advanced pancreatic cancer in a phase II trial (PACER).
    Citation
    Phase II trial of Cetuximab and conformal radiotherapy only in locally advanced pancreatic cancer with concurrent tissue sampling feasibility study. 2014, 7 (1):55-64 Transl Oncol
    Journal
    Translational Oncology
    URI
    http://hdl.handle.net/10541/320673
    PubMed ID
    24772208
    Type
    Article
    Language
    en
    ISSN
    1936-5233
    Collections
    All Christie Publications

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