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    Adjuvant bevacizumab in patients with melanoma at high risk of recurrence (AVAST-M): preplanned interim results from a multicentre, open-label, randomised controlled phase 3 study.

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    Authors
    Corrie, P
    Marshall, A
    Dunn, J
    Middleton, M
    Nathan, P
    Gore, M
    Davidson, N
    Nicholson, S
    Kelly, C
    Marples, M
    Danson, S
    Marshall, E
    Houston, S
    Board, R
    Waterston, A
    Nobes, J
    Harries, M
    Kumar, S
    Young, G
    Lorigan, Paul C
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    Affiliation
    Cambridge Cancer Trials Centre, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK.
    Issue Date
    2014-05
    
    Metadata
    Show full item record
    Abstract
    Bevacizumab, a monoclonal antibody that targets VEGF, has shown restricted activity in patients with advanced melanoma. We aimed to assess the role of bevacizumab as adjuvant treatment for patients with resected melanoma at high risk of recurrence. We report results from the preplanned interim analysis.
    Citation
    Adjuvant bevacizumab in patients with melanoma at high risk of recurrence (AVAST-M): preplanned interim results from a multicentre, open-label, randomised controlled phase 3 study. 2014, 15 (6):620-30 Lancet Oncol
    Journal
    The Lancet Oncology
    URI
    http://hdl.handle.net/10541/320613
    DOI
    10.1016/S1470-2045(14)70110-X
    PubMed ID
    24745696
    Type
    Article
    Language
    en
    ISSN
    1474-5488
    ae974a485f413a2113503eed53cd6c53
    10.1016/S1470-2045(14)70110-X
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