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    GATA3 shows differential immunohistochemical expression across thyroid and parathyroid lesions.

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    Authors
    Betts, Guy N J
    Beckett, Elizabeth
    Nonaka, Daisuke
    Issue Date
    2014-02-07
    
    Metadata
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    Abstract
    Transcription factors have proved highly specific immunohistochemical markers e.g. TTF-1 (thyroid/lung) and CDX-2 (Gastro-intestinal). GATA3 is a transcription factor which is functionally involved with the development of breast, urothelial, epidermal, T lymphocyte and parathyroid tissue. Recent studies of GATA3 immunoprofile, including that by Miettinen et al. across 2040 epithelial malignancies and 460 mesenchymal or neuroectodermal neoplasms, demonstrated the specificity and potential clinical utility of GATA3 across urothelial, mammary and cutaneous squamous lesions(1, 2) . This article is protected by copyright. All rights reserved.
    Citation
    GATA3 shows differential immunohistochemical expression across thyroid and parathyroid lesions. 2014: Histopathology
    Journal
    Histopathology
    URI
    http://hdl.handle.net/10541/314534
    DOI
    10.1111/his.12388
    PubMed ID
    24512009
    Type
    Article
    Language
    en
    ISSN
    1365-2559
    ae974a485f413a2113503eed53cd6c53
    10.1111/his.12388
    Scopus Count
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