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dc.contributor.authorCummings, Jeffrey
dc.contributor.authorMorris, Karen
dc.contributor.authorZhou, Cong
dc.contributor.authorSloane, Robert
dc.contributor.authorLancashire, Matthew
dc.contributor.authorMorris, Daniel
dc.contributor.authorBramley, Stephen
dc.contributor.authorKrebs, Matthew G
dc.contributor.authorKhoja, Leila
dc.contributor.authorDive, Caroline
dc.date.accessioned2013-12-20T11:47:44Z
dc.date.available2013-12-20T11:47:44Z
dc.date.issued2013
dc.identifier.citationMethod validation of circulating tumour cell enumeration at low cell counts. 2013, 13:415 BMC Canceren
dc.identifier.issn1471-2407
dc.identifier.pmid24024881
dc.identifier.doi10.1186/1471-2407-13-415
dc.identifier.urihttp://hdl.handle.net/10541/308814
dc.description.abstractCirculating tumour cells (CTC) are receiving increasing attention as prognostic, predictive and pharmacodynamic biomarkers in cancer patients. However, their clinical significance can be dependent on an accurate determination of CTC around cut-off values at low cell counts (<10 cells/7.5 ml). Consequently, we have conducted method validation of the CellSearch™ system focusing on clinical samples containing CTC in the cut-off region.
dc.language.isoenen
dc.rightsArchived with thanks to BMC canceren
dc.titleMethod validation of circulating tumour cell enumeration at low cell counts.en
dc.typeArticleen
dc.contributor.departmentClinical and Experimental Pharmacology Group, Paterson Institute for Cancer Research, Manchester Cancer Research Centre, University of Manchester, Manchester M20 4BX.en
dc.identifier.journalBMC Canceren
html.description.abstractCirculating tumour cells (CTC) are receiving increasing attention as prognostic, predictive and pharmacodynamic biomarkers in cancer patients. However, their clinical significance can be dependent on an accurate determination of CTC around cut-off values at low cell counts (<10 cells/7.5 ml). Consequently, we have conducted method validation of the CellSearch™ system focusing on clinical samples containing CTC in the cut-off region.


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