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    Method validation of circulating tumour cell enumeration at low cell counts.

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    Authors
    Cummings, Jeffrey
    Morris, Karen
    Zhou, Cong
    Sloane, Robert
    Lancashire, Matthew
    Morris, Daniel
    Bramley, Stephen
    Krebs, Matthew G
    Khoja, Leila
    Dive, Caroline
    Affiliation
    Clinical and Experimental Pharmacology Group, Paterson Institute for Cancer Research, Manchester Cancer Research Centre, University of Manchester, Manchester M20 4BX.
    Issue Date
    2013
    
    Metadata
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    Abstract
    Circulating tumour cells (CTC) are receiving increasing attention as prognostic, predictive and pharmacodynamic biomarkers in cancer patients. However, their clinical significance can be dependent on an accurate determination of CTC around cut-off values at low cell counts (<10 cells/7.5 ml). Consequently, we have conducted method validation of the CellSearch™ system focusing on clinical samples containing CTC in the cut-off region.
    Citation
    Method validation of circulating tumour cell enumeration at low cell counts. 2013, 13:415 BMC Cancer
    Journal
    BMC Cancer
    URI
    http://hdl.handle.net/10541/308814
    DOI
    10.1186/1471-2407-13-415
    PubMed ID
    24024881
    Type
    Article
    Language
    en
    ISSN
    1471-2407
    ae974a485f413a2113503eed53cd6c53
    10.1186/1471-2407-13-415
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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