Method validation of circulating tumour cell enumeration at low cell counts.
Authors
Cummings, JeffreyMorris, Karen
Zhou, Cong
Sloane, Robert
Lancashire, Matthew
Morris, Daniel
Bramley, Stephen
Krebs, Matthew G
Khoja, Leila
Dive, Caroline
Affiliation
Clinical and Experimental Pharmacology Group, Paterson Institute for Cancer Research, Manchester Cancer Research Centre, University of Manchester, Manchester M20 4BX.Issue Date
2013
Metadata
Show full item recordAbstract
Circulating tumour cells (CTC) are receiving increasing attention as prognostic, predictive and pharmacodynamic biomarkers in cancer patients. However, their clinical significance can be dependent on an accurate determination of CTC around cut-off values at low cell counts (<10 cells/7.5 ml). Consequently, we have conducted method validation of the CellSearch™ system focusing on clinical samples containing CTC in the cut-off region.Citation
Method validation of circulating tumour cell enumeration at low cell counts. 2013, 13:415 BMC CancerJournal
BMC CancerDOI
10.1186/1471-2407-13-415PubMed ID
24024881Type
ArticleLanguage
enISSN
1471-2407ae974a485f413a2113503eed53cd6c53
10.1186/1471-2407-13-415
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