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    De Novo treatment of diffuse large B-cell lymphoma with Rituximab, Cyclophosphamide, Vincristine, Gemcitabine, and Prednisolone in patients with cardiac comorbidity: A United Kingdom National Cancer Research Institute trial.

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    Authors
    Fields, P
    Townsend, W
    Webb, A
    Counsell, N
    Pocock, C
    Smith, P
    Jack, A
    El-Mehidi, N
    Johnson, P
    Radford, John A
    Linch, D
    Cunnningham, D
    Affiliation
    Guys and St Thomas' and King's College Hospitals, London, UK.
    Issue Date
    2013-11-12
    
    Metadata
    Show full item record
    Abstract
    The treatment of patients with diffuse large B-cell lymphoma (DLBCL) with cardiac comorbidity is problematic, because this group may not be able to receive anthracycline-containing chemoimmunotherapy. We designed a single-arm phase II multicenter trial of rituximab, gemcitabine, cyclophosphamide, vincristine, and prednisolone (R-GCVP) in patients considered unfit for anthracycline-containing chemoimmunotherapy because of cardiac comorbidity.
    Citation
    De Novo treatment of diffuse large B-cell lymphoma with Rituximab, Cyclophosphamide, Vincristine, Gemcitabine, and Prednisolone in patients with cardiac comorbidity: A United Kingdom National Cancer Research Institute trial. 2013: J Clin Oncol
    Journal
    Journal of Clinical Oncology
    URI
    http://hdl.handle.net/10541/308809
    DOI
    10.1200/JCO.2013.49.7586
    PubMed ID
    24220559
    Type
    Article
    Language
    en
    ISSN
    1527-7755
    ae974a485f413a2113503eed53cd6c53
    10.1200/JCO.2013.49.7586
    Scopus Count
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