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dc.contributor.authorOguejiofor, Kenneth K
dc.contributor.authorHall, J S
dc.contributor.authorMani, Navin
dc.contributor.authorDouglas, C
dc.contributor.authorSlevin, Nicholas J
dc.contributor.authorHomer, J
dc.contributor.authorHall, G
dc.contributor.authorWest, Catharine M L
dc.date.accessioned2013-12-20T10:14:13Z
dc.date.available2013-12-20T10:14:13Z
dc.date.issued2013-11
dc.identifier.citationThe prognostic significance of the biomarker p16 in oropharyngeal squamous cell carcinoma. 2013, 25 (11):630-8 Clin Oncolen
dc.identifier.issn1433-2981
dc.identifier.pmid23916365
dc.identifier.doi10.1016/j.clon.2013.07.003
dc.identifier.urihttp://hdl.handle.net/10541/308804
dc.description.abstractThere is an increasing incidence of human papillomavirus (HPV)-positive oropharyngeal squamous cell cancers (OPSCC) mostly associated with favourable outcomes. p16 immunohistochemistry is a surrogate marker for HPV positivity in OPSCC. The prognostic strength of p16 over traditional prognostic factors is not fully characterised. In this study, we evaluated the clinical and demographic differences between p16-positive and -negative OPSCC and characterised its prognostic strength versus traditional prognostic factors.
dc.language.isoenen
dc.rightsArchived with thanks to Clinical oncology (Royal College of Radiologists (Great Britain))en
dc.titleThe prognostic significance of the biomarker p16 in oropharyngeal squamous cell carcinoma.en
dc.typeArticleen
dc.contributor.departmentTranslational Radiobiology Group, Institute of Cancer Sciences, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.en
dc.identifier.journalClinical Oncologyen
html.description.abstractThere is an increasing incidence of human papillomavirus (HPV)-positive oropharyngeal squamous cell cancers (OPSCC) mostly associated with favourable outcomes. p16 immunohistochemistry is a surrogate marker for HPV positivity in OPSCC. The prognostic strength of p16 over traditional prognostic factors is not fully characterised. In this study, we evaluated the clinical and demographic differences between p16-positive and -negative OPSCC and characterised its prognostic strength versus traditional prognostic factors.


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