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    The prognostic significance of the biomarker p16 in oropharyngeal squamous cell carcinoma.

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    Authors
    Oguejiofor, Kenneth K
    Hall, J S
    Mani, Navin
    Douglas, C
    Slevin, Nicholas J
    Homer, J
    Hall, G
    West, Catharine M L
    Affiliation
    Translational Radiobiology Group, Institute of Cancer Sciences, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.
    Issue Date
    2013-11
    
    Metadata
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    Abstract
    There is an increasing incidence of human papillomavirus (HPV)-positive oropharyngeal squamous cell cancers (OPSCC) mostly associated with favourable outcomes. p16 immunohistochemistry is a surrogate marker for HPV positivity in OPSCC. The prognostic strength of p16 over traditional prognostic factors is not fully characterised. In this study, we evaluated the clinical and demographic differences between p16-positive and -negative OPSCC and characterised its prognostic strength versus traditional prognostic factors.
    Citation
    The prognostic significance of the biomarker p16 in oropharyngeal squamous cell carcinoma. 2013, 25 (11):630-8 Clin Oncol
    Journal
    Clinical Oncology
    URI
    http://hdl.handle.net/10541/308804
    DOI
    10.1016/j.clon.2013.07.003
    PubMed ID
    23916365
    Type
    Article
    Language
    en
    ISSN
    1433-2981
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.clon.2013.07.003
    Scopus Count
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