Fulvestrant plus anastrozole or placebo versus exemestane alone after progression on non-steroidal aromatase inhibitors in postmenopausal patients with hormone-receptor-positive locally advanced or metastatic breast cancer (SoFEA): a composite, multicentre, phase 3 randomised trial.
Authors
Johnston, SKilburn, L
Ellis, P
Dodwell, D
Cameron, D
Hayward, L
Im, Y-H
Braybrooke, J
Brunt, A
Cheung, K-L
Jyothirmayi, R
Robinson, A
Wardley, Andrew M
Wheatley, D
Howell, Anthony
Coombes, G
Sergenson, N
Sin, H-J
Folkerd, E
Dowsett, M
Bliss, J
Affiliation
Royal Marsden NHS Foundation Trust, London, UK. stephen.johnston@rmh.nhs.ukIssue Date
2013-09
Metadata
Show full item recordAbstract
The optimum endocrine treatment for postmenopausal women with advanced hormone-receptor-positive breast cancer that has progressed on non-steroidal aromatase inhibitors (NSAIs) is unclear. The aim of the SoFEA trial was to assess a maximum double endocrine targeting approach with the steroidal anti-oestrogen fulvestrant in combination with continued oestrogen deprivation.Citation
Fulvestrant plus anastrozole or placebo versus exemestane alone after progression on non-steroidal aromatase inhibitors in postmenopausal patients with hormone-receptor-positive locally advanced or metastatic breast cancer (SoFEA): a composite, multicentre, phase 3 randomised trial. 2013, 14 (10):989-98 Lancet OncolJournal
Lancet OncologyDOI
10.1016/S1470-2045(13)70322-XPubMed ID
23902874Type
ArticleLanguage
enISSN
1474-5488ae974a485f413a2113503eed53cd6c53
10.1016/S1470-2045(13)70322-X
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