Chemically facilitating the generation of diagnostic ions from SUMO(2/3) remnant isopeptides.
Affiliation
Paterson Institute for Cancer Research, University of Manchester, Wilmslow Road, Manchester, M20 4BX, UK; School of Chemistry, University of Manchester, Brunswick Street, Manchester, M13 9SU, UK.Issue Date
2013-09-30
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Mapping sites of wild-type SUMO modification is a challenging endeavour. Here we postulate that a combination of chemical derivatistation and collision-induced dissociation (CID) could be used to generate SUMO remnant diagnostic ions to aid both detection of these isopeptides and increase the analytical value of the product ion spectra required to characterize the nature and position of modification.Citation
Chemically facilitating the generation of diagnostic ions from SUMO(2/3) remnant isopeptides. 2013, 27 (18):2108-14 Rapid Commun Mass SpectromJournal
Rapid Communications in Mass SpectrometryDOI
10.1002/rcm.6670PubMed ID
23943332Type
ArticleLanguage
enISSN
1097-0231ae974a485f413a2113503eed53cd6c53
10.1002/rcm.6670
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