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    Chemically facilitating the generation of diagnostic ions from SUMO(2/3) remnant isopeptides.

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    Authors
    Chicooree, Navin
    Griffiths, John R
    Connolly, Yvonne
    Smith, Duncan L
    Affiliation
    Paterson Institute for Cancer Research, University of Manchester, Wilmslow Road, Manchester, M20 4BX, UK; School of Chemistry, University of Manchester, Brunswick Street, Manchester, M13 9SU, UK.
    Issue Date
    2013-09-30
    
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    Abstract
    Mapping sites of wild-type SUMO modification is a challenging endeavour. Here we postulate that a combination of chemical derivatistation and collision-induced dissociation (CID) could be used to generate SUMO remnant diagnostic ions to aid both detection of these isopeptides and increase the analytical value of the product ion spectra required to characterize the nature and position of modification.
    Citation
    Chemically facilitating the generation of diagnostic ions from SUMO(2/3) remnant isopeptides. 2013, 27 (18):2108-14 Rapid Commun Mass Spectrom
    Journal
    Rapid Communications in Mass Spectrometry
    URI
    http://hdl.handle.net/10541/302284
    DOI
    10.1002/rcm.6670
    PubMed ID
    23943332
    Type
    Article
    Language
    en
    ISSN
    1097-0231
    ae974a485f413a2113503eed53cd6c53
    10.1002/rcm.6670
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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