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    Dynamic contrast-enhanced MRI in patients with muscle-invasive transitional cell carcinoma of the bladder can distinguish between residual tumour and post-chemotherapy effect.

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    Authors
    Donaldson, Stephanie B
    Bonington, Suzanne C
    Kershaw, Lucy E
    Cowan, Richard A
    Lyons, Jeanette
    Elliott, Tony
    Carrington, Bernadette M
    Affiliation
    School of Cancer and Enabling Sciences, University of Manchester, Oxford Road, Manchester M13 9PL, UK; Christie Medical Physics and Engineering, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK.
    Issue Date
    2013-08-15
    
    Metadata
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    Abstract
    Treatment of muscle-invasive bladder cancer with chemotherapy results in haemorrhagic inflammation, mimicking residual tumour on conventional MR images and making interpretation difficult. The aim of this study was to use dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to estimate descriptive and tracer kinetic parameters post-neoadjuvant chemotherapy and to investigate whether parameters differed in areas of residual tumour and chemotherapy-induced haemorrhagic inflammation (treatment effect, Tr-Eff).
    Citation
    Dynamic contrast-enhanced MRI in patients with muscle-invasive transitional cell carcinoma of the bladder can distinguish between residual tumour and post-chemotherapy effect. 2013: Eur J Radiol
    Journal
    European Journal of Radiology
    URI
    http://hdl.handle.net/10541/302258
    DOI
    10.1016/j.ejrad.2013.08.008
    PubMed ID
    24034835
    Type
    Article
    Language
    en
    ISSN
    1872-7727
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.ejrad.2013.08.008
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