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    Epirubicin, oxaliplatin, and capecitabine with or without panitumumab for patients with previously untreated advanced oesophagogastric cancer (REAL3): a randomised, open-label phase 3 trial.

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    Authors
    Waddell, T
    Chau, I
    Cunningham, D
    Gonzalez, D
    Frances, A
    Okines, C
    Wotherspoon, A
    Saffery, C
    Middleton, G
    Wadsley, J
    Ferry, D
    Mansoor, Was
    Crosby, T
    Coxon, F
    Smith, D
    Waters, J
    Iveson, T
    Falk, S
    Slater, S
    Peckitt, C
    Barbachano, Y
    Show allShow less
    Affiliation
    The Royal Marsden NHS Foundation Trust, London and Surrey, UK.
    Issue Date
    2013-05
    
    Metadata
    Show full item record
    Abstract
    EGFR overexpression occurs in 27-55% of oesophagogastric adenocarcinomas, and correlates with poor prognosis. We aimed to assess addition of the anti-EGFR antibody panitumumab to epirubicin, oxaliplatin, and capecitabine (EOC) in patients with advanced oesophagogastric adenocarcinoma.
    Citation
    Epirubicin, oxaliplatin, and capecitabine with or without panitumumab for patients with previously untreated advanced oesophagogastric cancer (REAL3): a randomised, open-label phase 3 trial. 2013, 14 (6):481-9 Lancet Oncol
    Journal
    The Lancet Oncology
    URI
    http://hdl.handle.net/10541/295490
    DOI
    10.1016/S1470-2045(13)70096-2
    PubMed ID
    23594787
    Type
    Article
    Language
    en
    ISSN
    1474-5488
    ae974a485f413a2113503eed53cd6c53
    10.1016/S1470-2045(13)70096-2
    Scopus Count
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