Affiliation
Molecular Oncology Group, The Paterson Institute for Cancer Research, Manchester M20 4, UK.Issue Date
2013-06-10
Metadata
Show full item recordAbstract
The scaffold protein IQGAP1 regulates cell signaling through the RAF/MEK/ERK pathway. Recent data show that cancer cells in which the RAF/MEK/ERK pathway is activated are particularly sensitive to the disruption of IQGAP1 function. IQGAP drugs may be particularly effective in tumors that develop resistance to existing pathway drugs.Citation
Mind the IQGAP. 2013, 23 (6):715-7 Cancer CellJournal
Cancer CellDOI
10.1016/j.ccr.2013.05.017PubMed ID
23763998Type
ArticleLanguage
enISSN
1878-3686ae974a485f413a2113503eed53cd6c53
10.1016/j.ccr.2013.05.017