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dc.contributor.authorFarrell, Carole
dc.date.accessioned2013-07-08T14:58:06Z
dc.date.available2013-07-08T14:58:06Z
dc.date.issued2013
dc.identifier.citationBone metastases: assessment, management and treatment options. 2013, 22 (10):S4-S11 Br J Nursen_GB
dc.identifier.pmid23752365
dc.identifier.urihttp://hdl.handle.net/10541/295467
dc.description.abstractCancer cells from a primary tumour can spread to other parts of the body through the bloodstream or the lymphatic system. Bone metastases are common in multiple myeloma, where 70-80% of patients have bone metastases at diagnosis. They are also a common feature in solid tumours such as breast, lung, prostate, thyroid and renal carcinomas. The median survival in patients with bone metastases from breast cancer is 24 months; 20% of patients survive for 5 years or more. Pain is the most common symptom of bone metastases, which can often be severe and difficult to control. This article will discuss normal bone physiology and explain the changes that occur when cancer cells spread to bone. It will outline the signs and symptoms of bone metastases and discuss patient assessment, symptom management and treatment options, including different bisphosphonates. The physical and psychological impact of bone metastases should not be underestimated and nurses are well placed to improve the quality of life of patients.
dc.language.isoenen
dc.titleBone metastases: assessment, management and treatment options.en
dc.typeArticleen
dc.contributor.departmentThe Christie NHS Foundation Trust, Wilmslow Road, Withington, Manchester, M20 9BX, UKen_GB
dc.identifier.journalBritish Journal of Nursingen_GB
html.description.abstractCancer cells from a primary tumour can spread to other parts of the body through the bloodstream or the lymphatic system. Bone metastases are common in multiple myeloma, where 70-80% of patients have bone metastases at diagnosis. They are also a common feature in solid tumours such as breast, lung, prostate, thyroid and renal carcinomas. The median survival in patients with bone metastases from breast cancer is 24 months; 20% of patients survive for 5 years or more. Pain is the most common symptom of bone metastases, which can often be severe and difficult to control. This article will discuss normal bone physiology and explain the changes that occur when cancer cells spread to bone. It will outline the signs and symptoms of bone metastases and discuss patient assessment, symptom management and treatment options, including different bisphosphonates. The physical and psychological impact of bone metastases should not be underestimated and nurses are well placed to improve the quality of life of patients.


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