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    ETV2 expression marks blood and endothelium precursors, including hemogenic endothelium, at the onset of blood development.

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    Authors
    Wareing, Sarah
    Eliades, Alexia
    Lacaud, Georges
    Kouskoff, Valerie
    Affiliation
    Cancer Research UK Stem Cell Hematopoiesis Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, UK.
    Issue Date
    2012-09
    
    Metadata
    Show full item record
    Abstract
    ETV2 has been identified as an important player in embryonic hematopoiesis. However, the cell populations in which this transcription factor is expressed and operates during blood specification remain to be fully characterized. Here we address these issues using ES cells and a transgenic mouse line expressing green fluorescent protein (GFP) under the control of ETV2 regulatory elements, allowing us to observe the tight association between ETV2 expression and the initiation of hematopoiesis.
    Citation
    ETV2 expression marks blood and endothelium precursors, including hemogenic endothelium, at the onset of blood development. 2012, 241 (9):1454-64 Dev Dyn
    Journal
    Developmental Dynamics
    URI
    http://hdl.handle.net/10541/262495
    DOI
    10.1002/dvdy.23825
    PubMed ID
    22733530
    Type
    Article
    Language
    en
    ISSN
    1097-0177
    ae974a485f413a2113503eed53cd6c53
    10.1002/dvdy.23825
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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