ETV2 expression marks blood and endothelium precursors, including hemogenic endothelium, at the onset of blood development.
Affiliation
Cancer Research UK Stem Cell Hematopoiesis Group, Paterson Institute for Cancer Research, University of Manchester, Manchester, UK.Issue Date
2012-09
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Show full item recordAbstract
ETV2 has been identified as an important player in embryonic hematopoiesis. However, the cell populations in which this transcription factor is expressed and operates during blood specification remain to be fully characterized. Here we address these issues using ES cells and a transgenic mouse line expressing green fluorescent protein (GFP) under the control of ETV2 regulatory elements, allowing us to observe the tight association between ETV2 expression and the initiation of hematopoiesis.Citation
ETV2 expression marks blood and endothelium precursors, including hemogenic endothelium, at the onset of blood development. 2012, 241 (9):1454-64 Dev DynJournal
Developmental DynamicsDOI
10.1002/dvdy.23825PubMed ID
22733530Type
ArticleLanguage
enISSN
1097-0177ae974a485f413a2113503eed53cd6c53
10.1002/dvdy.23825
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