Outcomes of small-cell lung cancer patients treated with second-line chemotherapy: a multi-institutional retrospective analysis.
Authors
Garassino, M CTorri, V
Michetti, G
Lo Dico, M
La Verde, N
Aglione, S
Mancuso, A
Gallerani, E
Galetta, D
Martelli, O
Collovà, E
Fatigoni, S
Ghidini, A
Saggia, C
Bareggi, C
Rossi, A
Farina, G
Thatcher, Nick
Blackhall, Fiona H
Lorigan, Paul C
Califano, Raffaele
Affiliation
Oncology Department, Ospedale Fatebenefratelli e Oftalmico, Milano, Italy.Issue Date
2011-06
Metadata
Show full item recordAbstract
Patients with small-cell lung cancer (SCLC) that progress after first-line chemotherapy have a poor prognosis and the evidence of a benefit from second-line (SL) chemotherapy is limited. Patients relapsing or progressing more than 90 days after completion of first-line treatment are considered platinum sensitive and may be rechallenged with platinum-based chemotherapy. Topotecan is approved as SL treatment independent of time to progression. This retrospective analysis evaluates the clinical outcomes of SCLC patients who received SL chemotherapy after platinum-etoposide chemotherapy.Citation
Outcomes of small-cell lung cancer patients treated with second-line chemotherapy: a multi-institutional retrospective analysis. 2011, 72 (3):378-83 Lung CancerJournal
Lung CancerDOI
10.1016/j.lungcan.2010.09.009PubMed ID
20950888Type
ArticleLanguage
enISSN
1872-8332ae974a485f413a2113503eed53cd6c53
10.1016/j.lungcan.2010.09.009
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