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dc.contributor.authorTalbot, C
dc.contributor.authorTanteles, G
dc.contributor.authorBarnett, G
dc.contributor.authorBurnet, N
dc.contributor.authorChang-Claude, J
dc.contributor.authorColes, C
dc.contributor.authorDavidson, Susan E
dc.contributor.authorDunning, A
dc.contributor.authorMills, J
dc.contributor.authorMurray, R
dc.contributor.authorPopanda, O
dc.contributor.authorSeibold, P
dc.contributor.authorWest, Catharine M L
dc.contributor.authorYarnold, J
dc.contributor.authorSymonds, R
dc.date.accessioned2012-12-05T17:01:02Z
dc.date.available2012-12-05T17:01:02Z
dc.date.issued2012-08-07
dc.identifier.citationA replicated association between polymorphisms near TNFα and risk for adverse reactions to radiotherapy. 2012, 107 (4):748-53 Br J Canceren_GB
dc.identifier.issn1532-1827
dc.identifier.pmid22767148
dc.identifier.doi10.1038/bjc.2012.290
dc.identifier.urihttp://hdl.handle.net/10541/254634
dc.description.abstractResponse to radiotherapy varies between individuals both in terms of efficacy and adverse reactions. Finding genetic determinants of radiation response would allow the tailoring of the treatment, either by altering the radiation dose or by surgery. Despite a growing number of studies in radiogenomics, there are no well-replicated genetic association results.
dc.language.isoenen
dc.rightsArchived with thanks to British journal of canceren_GB
dc.subject.meshBreast Neoplasms
dc.subject.meshCohort Studies
dc.subject.meshFemale
dc.subject.meshGenetic Association Studies
dc.subject.meshHumans
dc.subject.meshPolymorphism, Single Nucleotide
dc.subject.meshRadiation Injuries
dc.subject.meshRadiotherapy
dc.subject.meshRisk
dc.subject.meshTumor Necrosis Factor-alpha
dc.titleA replicated association between polymorphisms near TNFα and risk for adverse reactions to radiotherapy.en
dc.typeArticleen
dc.contributor.departmentDepartment of Genetics, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK.en_GB
dc.identifier.journalBritish Journal of Canceren_GB
html.description.abstractResponse to radiotherapy varies between individuals both in terms of efficacy and adverse reactions. Finding genetic determinants of radiation response would allow the tailoring of the treatment, either by altering the radiation dose or by surgery. Despite a growing number of studies in radiogenomics, there are no well-replicated genetic association results.


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