A replicated association between polymorphisms near TNFα and risk for adverse reactions to radiotherapy.
Davidson, Susan E
West, Catharine M L
AffiliationDepartment of Genetics, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK.
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AbstractResponse to radiotherapy varies between individuals both in terms of efficacy and adverse reactions. Finding genetic determinants of radiation response would allow the tailoring of the treatment, either by altering the radiation dose or by surgery. Despite a growing number of studies in radiogenomics, there are no well-replicated genetic association results.
CitationA replicated association between polymorphisms near TNFα and risk for adverse reactions to radiotherapy. 2012, 107 (4):748-53 Br J Cancer
JournalBritish Journal of Cancer