Enhanced stability of microRNA expression facilitates classification of FFPE tumour samples exhibiting near total mRNA degradation.
AuthorsHall, J S
Valentine, Helen R
Irlam, Joely J
Hoskin, P J
Miller, Crispin J
West, Catharine M L
AffiliationTranslational Radiobiology Group, School of Cancer and Enabling Sciences, Manchester Academic Health Science Centre, The University of Manchester, Christie Hospital NHS Trust, Wilmslow Road, Manchester M20 4BX, UK.
MetadataShow full item record
AbstractAs degradation of formalin-fixed paraffin-embedded (FFPE) samples limits the ability to profile mRNA expression, we explored factors predicting the success of mRNA expression profiling of FFPE material and investigated an approach to overcome the limitation.
CitationEnhanced stability of microRNA expression facilitates classification of FFPE tumour samples exhibiting near total mRNA degradation. 2012, 107 (4):684-94 Br J Cancer
JournalBritish Journal of Cancer