Enhanced stability of microRNA expression facilitates classification of FFPE tumour samples exhibiting near total mRNA degradation.
Authors
Hall, J STaylor, J
Valentine, Helen R
Irlam, Joely J
Eustace, A
Hoskin, P J
Miller, Crispin J
West, Catharine M L
Affiliation
Translational Radiobiology Group, School of Cancer and Enabling Sciences, Manchester Academic Health Science Centre, The University of Manchester, Christie Hospital NHS Trust, Wilmslow Road, Manchester M20 4BX, UK.Issue Date
2012-08-07
Metadata
Show full item recordAbstract
As degradation of formalin-fixed paraffin-embedded (FFPE) samples limits the ability to profile mRNA expression, we explored factors predicting the success of mRNA expression profiling of FFPE material and investigated an approach to overcome the limitation.Citation
Enhanced stability of microRNA expression facilitates classification of FFPE tumour samples exhibiting near total mRNA degradation. 2012, 107 (4):684-94 Br J CancerJournal
British Journal of CancerDOI
10.1038/bjc.2012.294PubMed ID
22805332Type
ArticleLanguage
enISSN
1532-1827ae974a485f413a2113503eed53cd6c53
10.1038/bjc.2012.294