The differential effects of statins on the metastatic behaviour of prostate cancer.
Authors
Brown, Michael DHart, C
Tawadros, T
Ramani, Vijay A C
Sangar, Vijay K
Lau, Maurice W
Clarke, Noel W
Affiliation
Genito Urinary Cancer Research Group, University of Manchester, Paterson Institute for Cancer Research, Manchester Academic Health Science Centre, The Christie NHS Foundation Trust, Wilmslow Road, Withington, Manchester M20 4BX, UK. mbrown@picr.man.ac.ukIssue Date
2012-05-08
Metadata
Show full item recordAbstract
Although statins do not affect the incidence of prostate cancer (CaP), usage reduces the risk of clinical progression and mortality. Although statins are known to downregulate the mevalonate pathway, the mechanism by which statins reduce CaP progression is unknown.Citation
The differential effects of statins on the metastatic behaviour of prostate cancer. 2012, 106 (10):1689-96 Br J CancerJournal
British Journal of CancerDOI
10.1038/bjc.2012.138PubMed ID
22531631Type
ArticleLanguage
enISSN
1532-1827ae974a485f413a2113503eed53cd6c53
10.1038/bjc.2012.138
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