Using prior information from the medical literature in GWAS of oral cancer identifies novel susceptibility variant on chromosome 4--the AdAPT method.
Authors
Johansson, MRoberts, A
Chen, D
Li, Yaoyong
Delahaye-Sourdeix, M
Aswani, N
Greenwood, M
Benhamou, S
Lagiou, P
Holcátová, I
Richiardi, L
Kjaerheim, K
Agudo, A
Castellsagué, X
Macfarlane, T
Barzan, L
Canova, C
Thakker, N
Conway, D
Znaor, A
Healy, C
Ahrens, W
Zaridze, D
Szeszenia-Dabrowska, N
Lissowska, J
Fabiánová, E
Mates, I
Bencko, V
Foretova, L
Janout, V
Curado, M
Koifman, S
Menezes,
Wünsch-Filho, V
Eluf-Neto, J
Boffetta, P
Franceschi, S
Herrero, R
Fernandez Garrote, L
Talamini, R
Boccia, S
Galan, P
Vatten, L
Thomson, P
Zelenika, D
Lathrop, M
Byrnes, G
Cunningham, H
Brennan, Paul
Wakefield, J
McKay, J
Affiliation
Section of Genetics, International Agency for Research on Cancer (IARC), Lyon, France.Issue Date
2012
Metadata
Show full item recordAbstract
Genome-wide association studies (GWAS) require large sample sizes to obtain adequate statistical power, but it may be possible to increase the power by incorporating complementary data. In this study we investigated the feasibility of automatically retrieving information from the medical literature and leveraging this information in GWAS.Citation
Using prior information from the medical literature in GWAS of oral cancer identifies novel susceptibility variant on chromosome 4--the AdAPT method. 2012, 7 (5):e36888 PLoS ONEJournal
PloS OneDOI
10.1371/journal.pone.0036888PubMed ID
22662130Type
ArticleLanguage
enISSN
1932-6203ae974a485f413a2113503eed53cd6c53
10.1371/journal.pone.0036888
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