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    A phase I study to determine the safety, pharmacokinetics and pharmacodynamics of a dual VEGFR and FGFR inhibitor, brivanib, in patients with advanced or metastatic solid tumors.

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    Authors
    Jonker, D J
    Rosen, L S
    Sawyer, M B
    de Braud, F
    Wilding, G
    Sweeney, C J
    Jayson, Gordon C
    McArthur, G A
    Rustin, G
    Goss, G
    Kantor, J
    Velasquez, L
    Syed, S
    Mokliatchouk, O
    Feltquate, D M
    Kollia, G
    Nuyten, D S A
    Galbraith, S
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    Affiliation
    Division of Medical Oncology, Ottawa Hospital Cancer Centre, University of Ottawa, Ottawa, Canada.
    Issue Date
    2011-06
    
    Metadata
    Show full item record
    Abstract
    This study was designed to determine the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of brivanib in patients with advanced/metastatic solid tumors.
    Citation
    A phase I study to determine the safety, pharmacokinetics and pharmacodynamics of a dual VEGFR and FGFR inhibitor, brivanib, in patients with advanced or metastatic solid tumors. 2011, 22 (6):1413-9 Ann Oncol
    Journal
    Annals of Oncology
    URI
    http://hdl.handle.net/10541/230943
    DOI
    10.1093/annonc/mdq599
    PubMed ID
    21131369
    Type
    Article
    Language
    en
    ISSN
    1569-8041
    ae974a485f413a2113503eed53cd6c53
    10.1093/annonc/mdq599
    Scopus Count
    Collections
    All Christie Publications
    Medical Oncology

    entitlement

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