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dc.contributor.authorLee, Rana
dc.contributor.authorSlevin, Nicholas J
dc.contributor.authorMusgrove, Brian
dc.contributor.authorSwindell, Ric
dc.contributor.authorMolassiotis, Alexander
dc.date.accessioned2012-06-27T08:47:23Z
dc.date.available2012-06-27T08:47:23Z
dc.date.issued2011-07-25
dc.identifier.citationPrediction of post-treatment trismus in head and neck cancer patients. 2011: Br J Oral Maxillofac Surgen_GB
dc.identifier.issn1532-1940
dc.identifier.pmid21794962
dc.identifier.doi10.1016/j.bjoms.2011.06.009
dc.identifier.urihttp://hdl.handle.net/10541/230912
dc.description.abstractOur aim was to establish the incidence of trismus over time, together with risk factors (including quality of life (QoL)) for the prediction of trismus after treatment in patients with cancer of the head and neck. It was a longitudinal study of 152 patients accepted for primary operation who attended the head and neck cancer clinic of a tertiary referral cancer centre in the United Kingdom. A total of 87 patients was studied prospectively. Our results showed that 41/87 (47%) of patients presented with trismus, 57/80 (71%) had postoperative trismus, and 41/52 (79%) had trismus 6 months after operation or radiotherapy (trismus defined as a maximum mouth opening of ≤35mm). Men and those who drank a lot of alcohol were less likely to have trismus after treatment. QoL variables showed that pain, eating, chewing, taste, saliva, social functioning, social contact, and dry mouth were significantly more impaired in the trismus group than among those without trismus. Postoperative differences in QoL between the two groups highlighted problems with social function and role-playing, fatigue, activity, recreation, and overall reduction in QoL. Women, and those who do not drink alcohol, are at particularly high risk of developing trismus, and, to prevent it and treat it, patients may benefit from multidisciplinary management at an early stage during treatment.
dc.languageENG
dc.language.isoenen
dc.rightsArchived with thanks to The British journal of oral & maxillofacial surgeryen_GB
dc.titlePrediction of post-treatment trismus in head and neck cancer patients.en
dc.typeArticleen
dc.contributor.departmentChristie Hospital NHS Trust, Manchester M20 4BX, UK.en_GB
dc.identifier.journalBritish Journal of Oral & Maxillofacial Surgeryen_GB
html.description.abstractOur aim was to establish the incidence of trismus over time, together with risk factors (including quality of life (QoL)) for the prediction of trismus after treatment in patients with cancer of the head and neck. It was a longitudinal study of 152 patients accepted for primary operation who attended the head and neck cancer clinic of a tertiary referral cancer centre in the United Kingdom. A total of 87 patients was studied prospectively. Our results showed that 41/87 (47%) of patients presented with trismus, 57/80 (71%) had postoperative trismus, and 41/52 (79%) had trismus 6 months after operation or radiotherapy (trismus defined as a maximum mouth opening of ≤35mm). Men and those who drank a lot of alcohol were less likely to have trismus after treatment. QoL variables showed that pain, eating, chewing, taste, saliva, social functioning, social contact, and dry mouth were significantly more impaired in the trismus group than among those without trismus. Postoperative differences in QoL between the two groups highlighted problems with social function and role-playing, fatigue, activity, recreation, and overall reduction in QoL. Women, and those who do not drink alcohol, are at particularly high risk of developing trismus, and, to prevent it and treat it, patients may benefit from multidisciplinary management at an early stage during treatment.


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