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    A phase 2 study of SP1049C, doxorubicin in P-glycoprotein-targeting pluronics, in patients with advanced adenocarcinoma of the esophagus and gastroesophageal junction.

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    Authors
    Valle, Juan W
    Armstrong, Anne C
    Newman, C
    Alakhov, V
    Pietrzynski, G
    Brewer, Julie
    Campbell, S
    Corrie, P
    Rowinsky, E K
    Ranson, Malcolm R
    Affiliation
    Department of Medical Oncology, Christie Hospital NHS Trust, Wilmslow Road, Manchester M20 4BX, UK. juan.valle@christie.nhs.uk
    Issue Date
    2011-10
    
    Metadata
    Show full item record
    Abstract
    To evaluate the antitumor activity of SP1049C, a novel P-glycoprotein targeting micellar formulation of doxorubicin, consisting of doxorubicin and two non-ionic block copolymers (pluronics), in patients with advanced adenocarcinoma of the esophagus and gastroesophageal junction (GEJ). Patients and
    Citation
    A phase 2 study of SP1049C, doxorubicin in P-glycoprotein-targeting pluronics, in patients with advanced adenocarcinoma of the esophagus and gastroesophageal junction. 2011, 29 (5):1029-37 Invest New Drugs
    Journal
    Investigational New Drugs
    URI
    http://hdl.handle.net/10541/226381
    DOI
    10.1007/s10637-010-9399-1
    PubMed ID
    20179989
    Type
    Article
    Language
    en
    ISSN
    1573-0646
    ae974a485f413a2113503eed53cd6c53
    10.1007/s10637-010-9399-1
    Scopus Count
    Collections
    All Christie Publications
    Medical Oncology

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