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dc.contributor.authorMackenzie, S
dc.contributor.authorCraven, T
dc.contributor.authorGattamaneni, Rao
dc.contributor.authorSwindell, Ric
dc.contributor.authorShalet, Stephen M
dc.contributor.authorBrabant, Georg E
dc.date.accessioned2012-05-28T11:59:04Z
dc.date.available2012-05-28T11:59:04Z
dc.date.issued2011-09
dc.identifier.citationLong-term safety of growth hormone replacement after CNS irradiation. 2011, 96 (9):2756-61 J Clin Endocrinol Metaben_GB
dc.identifier.issn1945-7197
dc.identifier.pmid21715535
dc.identifier.doi10.1210/jc.2011-0112
dc.identifier.urihttp://hdl.handle.net/10541/226215
dc.description.abstractRadiotherapy is a central component in the treatment of many brain tumors, but long-term sequelae include GH deficiency and increased risk of secondary neoplasms. It is unclear whether replacement therapy with GH (GHRT) further increases this risk.
dc.language.isoenen
dc.rightsArchived with thanks to The Journal of clinical endocrinology and metabolismen_GB
dc.subject.meshAdenoma
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshBrain Neoplasms
dc.subject.meshCase-Control Studies
dc.subject.meshCranial Irradiation
dc.subject.meshFemale
dc.subject.meshHormone Replacement Therapy
dc.subject.meshHuman Growth Hormone
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshNeoplasm Recurrence, Local
dc.subject.meshPituitary Neoplasms
dc.subject.meshRetrospective Studies
dc.subject.meshRisk
dc.titleLong-term safety of growth hormone replacement after CNS irradiation.en
dc.typeArticleen
dc.contributor.departmentDepartment of Endocrinology, The Christie, Manchester Academic Health Science Centre, Wilmslow Road, Manchester M20 4BX, United Kingdom.en_GB
dc.identifier.journalJournal of Clinical Endocrinology and Metabolismen_GB
html.description.abstractRadiotherapy is a central component in the treatment of many brain tumors, but long-term sequelae include GH deficiency and increased risk of secondary neoplasms. It is unclear whether replacement therapy with GH (GHRT) further increases this risk.


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