Long-term safety of growth hormone replacement after CNS irradiation.
AffiliationDepartment of Endocrinology, The Christie, Manchester Academic Health Science Centre, Wilmslow Road, Manchester M20 4BX, United Kingdom.
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AbstractRadiotherapy is a central component in the treatment of many brain tumors, but long-term sequelae include GH deficiency and increased risk of secondary neoplasms. It is unclear whether replacement therapy with GH (GHRT) further increases this risk.
CitationLong-term safety of growth hormone replacement after CNS irradiation. 2011, 96 (9):2756-61 J Clin Endocrinol Metab
JournalJournal of Clinical Endocrinology and Metabolism