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    R1507, a monoclonal antibody to the insulin-like growth factor 1 receptor, in patients with recurrent or refractory Ewing sarcoma family of tumors: results of a phase II Sarcoma Alliance for Research through Collaboration study.

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    Authors
    Pappo, A
    Patel, S
    Crowley, J
    Reinke, D
    Kuenkele, K
    Chawla, S
    Toner, G
    Maki, R
    Meyers, P
    Chugh, R
    Ganjoo, K
    Schuetze, S
    Juergens, H
    Leahy, Michael G
    Geoerger, B
    Benjamin, R
    Helman, L
    Baker, L
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    Affiliation
    St Jude Children’s Research Hospital, Memphis, TN, USA.
    Issue Date
    2011-12-01
    
    Metadata
    Show full item record
    Abstract
    The type 1 insulin-like growth factor 1 receptor (IGF-1R) has been implicated in the pathogenesis of the Ewing sarcoma family of tumors (ESFT). We conducted a multicenter phase II study of the fully human IGF-1R monoclonal antibody R1507 in patients with recurrent or refractory ESFT.
    Citation
    R1507, a monoclonal antibody to the insulin-like growth factor 1 receptor, in patients with recurrent or refractory Ewing sarcoma family of tumors: results of a phase II Sarcoma Alliance for Research through Collaboration study. 2011, 29 (34):4541-7 J Clin Oncol
    Journal
    Journal of Clinical Oncology
    URI
    http://hdl.handle.net/10541/221552
    DOI
    10.1200/JCO.2010.34.0000
    PubMed ID
    22025149
    Type
    Article
    Language
    en
    ISSN
    1527-7755
    ae974a485f413a2113503eed53cd6c53
    10.1200/JCO.2010.34.0000
    Scopus Count
    Collections
    All Christie Publications
    Medical Oncology

    entitlement

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