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dc.contributor.authorSebastian, A
dc.contributor.authorAllan, Ernest
dc.contributor.authorAllan, Donald
dc.contributor.authorColthurst, J
dc.contributor.authorBayat, A
dc.date.accessioned2012-03-22T13:36:37Z
dc.date.available2012-03-22T13:36:37Z
dc.date.issued2011-12
dc.identifier.citationAddition of novel degenerate electrical waveform stimulation with photodynamic therapy significantly enhances its cytotoxic effect in keloid fibroblasts: first report of a potential combination therapy. 2011, 64 (3):174-84 J Dermatol Scien_GB
dc.identifier.issn1873-569X
dc.identifier.pmid22015050
dc.identifier.doi10.1016/j.jdermsci.2011.08.012
dc.identifier.urihttp://hdl.handle.net/10541/216294
dc.description.abstractWe recently reported use of photodynamic therapy (PDT) for treating keloid disease (KD). However, in view of high recurrence rates post any treatment modality, adjuvant therapies should be considered. Additionally, we previously demonstrated the effect of a novel electrical waveform, the degenerate wave (DW) on differential gene expression in keloid fibroblasts.
dc.language.isoenen
dc.rightsArchived with thanks to Journal of dermatological scienceen_GB
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshAminolevulinic Acid
dc.subject.meshApoptosis
dc.subject.meshBlotting, Western
dc.subject.meshCase-Control Studies
dc.subject.meshCaspase 3
dc.subject.meshCell Proliferation
dc.subject.meshCells, Cultured
dc.subject.meshCollagen Type I
dc.subject.meshCollagen Type III
dc.subject.meshCombined Modality Therapy
dc.subject.meshElectric Stimulation Therapy
dc.subject.meshEnzyme Activation
dc.subject.meshFemale
dc.subject.meshFibroblasts
dc.subject.meshFlow Cytometry
dc.subject.meshGene Expression Regulation
dc.subject.meshHumans
dc.subject.meshKeloid
dc.subject.meshL-Lactate Dehydrogenase
dc.subject.meshMale
dc.subject.meshMatrix Metalloproteinase 2
dc.subject.meshMembrane Potential, Mitochondrial
dc.subject.meshMiddle Aged
dc.subject.meshNecrosis
dc.subject.meshPhotochemotherapy
dc.subject.meshPhotosensitizing Agents
dc.subject.meshPolymerase Chain Reaction
dc.subject.meshProtoporphyrins
dc.subject.meshReactive Oxygen Species
dc.subject.meshTime Factors
dc.titleAddition of novel degenerate electrical waveform stimulation with photodynamic therapy significantly enhances its cytotoxic effect in keloid fibroblasts: first report of a potential combination therapy.en
dc.typeArticleen
dc.contributor.departmentPlastic & Reconstructive Surgery Research, School of Translational Medicine, Manchester Interdisciplinary Biocentre (MIB), The University of Manchester, UK.en_GB
dc.identifier.journalJournal of Dermatological Scienceen_GB
html.description.abstractWe recently reported use of photodynamic therapy (PDT) for treating keloid disease (KD). However, in view of high recurrence rates post any treatment modality, adjuvant therapies should be considered. Additionally, we previously demonstrated the effect of a novel electrical waveform, the degenerate wave (DW) on differential gene expression in keloid fibroblasts.


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