Parotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial.
Urbano, Teresa G
Bhide, S A
Miles, E A
Miah, A B
Tanay, M A
Jefferies, S J
Yap, Beng K
Sydenham, M A
AffiliationHead and Neck Unit, Royal Marsden Hospitals NHS Foundation Trust, London, UK.
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AbstractXerostomia is the most common late side-effect of radiotherapy to the head and neck. Compared with conventional radiotherapy, intensity-modulated radiotherapy (IMRT) can reduce irradiation of the parotid glands. We assessed the hypothesis that parotid-sparing IMRT reduces the incidence of severe xerostomia.
CitationParotid-sparing intensity modulated versus conventional radiotherapy in head and neck cancer (PARSPORT): a phase 3 multicentre randomised controlled trial. 2011, 12 (2):127-36 Lancet Oncol.
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