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    Clinical and immunological response to photodynamic therapy in the treatment of vulval intraepithelial neoplasia.

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    Authors
    Daayana, S
    Winters, U
    Stern, Peter L
    Kitchener, H C
    Affiliation
    Department of Gynaecology, St Marys Hospital, Manchester, United Kingdom.
    Issue Date
    2011-05
    
    Metadata
    Show full item record
    Abstract
    Vulval intraepithelial neoplasia (VIN) is a premalignant condition of the vulva and its incidence is increasing. The common type of VIN is associated with oncogenic types of human papilloma virus (HPV) infection. The standard modalities of treatment for VIN, surgical excision and laser ablation, are both sub-optimal, associated with high rates of disease recurrence. There is a need for non-surgical treatment options for VIN and photodynamic therapy (PDT), by altering the local immunological parameters, has the potential to clear both VIN and HPV. This article reviews the studies of PDT treatment for VIN and discusses the clinical and immunological responses to PDT treatment in the various studies.
    Citation
    Clinical and immunological response to photodynamic therapy in the treatment of vulval intraepithelial neoplasia. 2011, 10 (5):802-9 Photochem. Photobiol. Sci.
    Journal
    Photochemical & Photobiological Sciences
    URI
    http://hdl.handle.net/10541/200932
    DOI
    10.1039/c0pp00344a
    PubMed ID
    21494722
    Type
    Article
    Language
    en
    ISSN
    1474-9092
    ae974a485f413a2113503eed53cd6c53
    10.1039/c0pp00344a
    Scopus Count
    Collections
    All Paterson Institute for Cancer Research

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