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    Phase I pharmacokinetic and pharmacodynamic study of the bioreductive drug RH1.

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    Authors
    Danson, Sarah
    Johnson, P
    Ward, Timothy H
    Dawson, M
    Denneny, Olive
    Dickinson, G
    Aarons, Leon
    Watson, A
    Jowle, Debra
    Cummings, Jeffrey
    Robson, L
    Halbert, G
    Dive, Caroline
    Ranson, Malcolm R
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    Affiliation
    Department of Medical Oncology, University of Manchester, Christie Hospital NHS Foundation Trust, Manchester, UK.
    Issue Date
    2011-07
    
    Metadata
    Show full item record
    Abstract
    This trial describes a first-in-man evaluation of RH1, a novel bioreductive drug activated by DT-diaphorase (DTD), an enzyme overexpressed in many tumours.
    Citation
    Phase I pharmacokinetic and pharmacodynamic study of the bioreductive drug RH1. 2011, 22 (7):1653-60 Ann. Oncol.
    Journal
    Annals of Oncology
    URI
    http://hdl.handle.net/10541/200921
    DOI
    10.1093/annonc/mdq638
    PubMed ID
    21378203
    Type
    Article
    Language
    en
    ISSN
    1569-8041
    ae974a485f413a2113503eed53cd6c53
    10.1093/annonc/mdq638
    Scopus Count
    Collections
    All Christie Publications
    All Paterson Institute for Cancer Research
    Medical Oncology

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