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    Clinical neurological outcome and quality of life among patients with limited small-cell cancer treated with two different doses of prophylactic cranial irradiation in the intergroup phase III trial (PCI99-01, EORTC 22003-08004, RTOG 0212 and IFCT 99-01).

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    Authors
    Le Péchoux, C
    Laplanche, A
    Faivre-Finn, Corinne
    Ciuleanu, T
    Wanders, R
    Lerouge, D
    Keus, R
    Hatton, M
    Videtic, G M
    Senan, S
    Wolfson, A
    Jones, R
    Arriagada, R
    Quoix, E
    Dunant, A
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    Affiliation
    Radiation Oncology Department, Institut Gustave-Roussy, Villejuif, France.
    Issue Date
    2011-05
    
    Metadata
    Show full item record
    Abstract
    We recently published the results of the PCI99 randomised trial comparing the effect of a prophylactic cranial irradiation (PCI) at 25 or 36 Gy on the incidence of brain metastases (BM) in 720 patients with limited small-cell lung cancer (SCLC). As concerns about neurotoxicity were a major issue surrounding PCI, we report here midterm and long-term repeated evaluation of neurocognitive functions and quality of life (QoL).
    Citation
    Clinical neurological outcome and quality of life among patients with limited small-cell cancer treated with two different doses of prophylactic cranial irradiation in the intergroup phase III trial (PCI99-01, EORTC 22003-08004, RTOG 0212 and IFCT 99-01). 2011, 22 (5):1154-63 Ann. Oncol.
    Journal
    Annals of Oncology
    URI
    http://hdl.handle.net/10541/200251
    DOI
    10.1093/annonc/mdq576
    PubMed ID
    21139020
    Type
    Article
    Language
    en
    ISSN
    1569-8041
    ae974a485f413a2113503eed53cd6c53
    10.1093/annonc/mdq576
    Scopus Count
    Collections
    All Christie Publications
    Clinical Oncology

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