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    Sorafenib and dacarbazine as first-line therapy for advanced melanoma: phase I and open-label phase II studies.

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    Authors
    Eisen, T
    Marais, R
    Affolter, A
    Lorigan, Paul C
    Robert, C
    Corrie, P
    Ottensmeier, C
    Chevreau, C
    Chao, D
    Nathan, P D
    Jouary, T
    Harries, M
    Negrier, S
    Montegriffo, E
    Ahmad, T
    Gibbens, I
    James, M G
    Strauss, U P
    Prendergast, S
    Gore, M E
    Show allShow less
    Affiliation
    Department of Oncology (R4), Cambridge Biomedical Research Centre, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK. tgqe2@cam.ac.uk
    Issue Date
    2011-07-26
    
    Metadata
    Show full item record
    Abstract
    The safety of oral sorafenib up to a maximum protocol-specified dose combined with dacarbazine in patients with metastatic, histologically confirmed melanoma was investigated in a phase I dose-escalation study and the activity of the combination was explored in an open-label phase II study.
    Citation
    Sorafenib and dacarbazine as first-line therapy for advanced melanoma: phase I and open-label phase II studies. 2011, 105 (3):353-9 Br. J. Cancer
    Journal
    British Journal of Cancer
    URI
    http://hdl.handle.net/10541/200169
    DOI
    10.1038/bjc.2011.257
    PubMed ID
    21750549
    PubMed Central ID
    PMC3172912
    Type
    Article
    Language
    en
    ISSN
    1532-1827
    ae974a485f413a2113503eed53cd6c53
    10.1038/bjc.2011.257
    Scopus Count
    Collections
    All Christie Publications
    Medical Oncology

    entitlement

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