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    Growth impairment in children treated for brain tumours.

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    Authors
    Shalet, Stephen M
    Beardwell, Colin G
    Aarons, B M
    Pearson, D
    Morris Jones, P H
    Affiliation
    Christie Hospital, Withington, Manchester, M20 4BX, UK
    Issue Date
    1978-06
    
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    Abstract
    Growth and growth hormone (GH) secretion were studied in 14 children with brain tumours before radiation and chemotherapy and at various time intervals afterwards. The peak GH response to hypoglycaemia was normal in all patients before radiation. In 6 patients the peak GH response was impaired 1 year after radiation, and in a seventh it was normal at 1 year but impaired 2 years after radiation. In 12 of 13 patients the growth velocity during the first year of chemotherapy was below the 3rd centile, although none of these had an initial standing height below the 3rd centile. Thus it appears that poor growth in such children occurs irrespective of whether radiation-induced GH deficiency develops. The cause of this impaired growth is unknown.
    Citation
    Growth impairment in children treated for brain tumours. 1978, 53 (6):491-4 Arch. Dis. Child.
    Journal
    Archives of Disease in Childhood
    URI
    http://hdl.handle.net/10541/200131
    DOI
    10.1136/adc.53.6.491
    PubMed ID
    686776
    Type
    Article
    Language
    en
    ISSN
    1468-2044
    ae974a485f413a2113503eed53cd6c53
    10.1136/adc.53.6.491
    Scopus Count
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