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    Effect of surgery on tumour-directed leucocyte responses.

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    Authors
    Vose, Brent M
    Moudgil, G C
    Affiliation
    Paterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester
    Issue Date
    1975-01-11
    
    Metadata
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    Abstract
    Leucocytes from 22 out of 26 patients with mammary carcinoma were significantly cytotoxic in vitro for cells cultured from mammary tumours though only two out of 17 of these preparations were cytotoxic for cells cultured from tumours arising at other sites. In the immediate postoperative period reactivity of patients' leucocytes with mammary tumour cells was undetectable but returned within one week of surgery. Leucocyte cytotoxicity may therefore offer a model in which the mechanism of postoperative depression of immunological competence may be investigated.
    Citation
    Effect of surgery on tumour-directed leucocyte responses. 1975, 1 (5949):56-8 Br Med J
    Journal
    British Medical Journal
    URI
    http://hdl.handle.net/10541/198677
    DOI
    10.1136/bmj.1.5949.56
    PubMed ID
    1109658
    Type
    Article
    Language
    en
    ISSN
    0007-1447
    ae974a485f413a2113503eed53cd6c53
    10.1136/bmj.1.5949.56
    Scopus Count
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    All Paterson Institute for Cancer Research

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