Electron spin resonance study of changes during the development of a mouse myeloid leukaemia. I. Paramagnetic metal ions.
AuthorsDodd, Nicholas J F
AffiliationPaterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester
MetadataShow full item record
AbstractThe blood, spleen and liver of mice were examined by means of electron spin resonance (e.s.r.), throughout the course of myeloid leukaemia induced by intravenous injection of leukaemic spleen cells. In blood, marked increases in the concentrations of iron transferrin and ceruloplasmin occurred within the first 3 days after injection. In the spleen, changes in the concentrations of paramagnetic copper and iron complexes were detectable by about the 5th day, before any measurable splenic enlargement, whilst in the liver changes were detectable by about the 8th day. The changes occurring in blood, spleen and liver during the development of leukaemia appear to be related and they are discussed in terms of iron transport.
CitationElectron spin resonance study of changes during the development of a mouse myeloid leukaemia. I. Paramagnetic metal ions. 1975, 32 (1):108-20 Br. J. Cancer
JournalBritish Journal of Cancer
PubMed Central IDPMC2024794
- ESR study of development of RFM/Un murine myeloid leukaemia.
- Authors: Dodd NJ, Silcock JM
- Issue date: 1978 Nov
- Electron spin resonance study of changes during the development of a mouse myeloid leukaemia. II. The ascorbyl radical.
- Authors: Dodd NJ, Giron-Conland JM
- Issue date: 1975 Oct
- [Time- and dose-dependent post-irradiation changes of Fe3+-transferrin and Cu2+-ceruloplasmin pools in blood, their influence on ribonucleotide reductase activity in animal tissues and the effects of radioprotectors].
- Authors: Sharygin VL, Pulatova MK, Shliakova TG, Todorov IN
- Issue date: 2003 Nov-Dec
- Electron spin resonance studies on caeruloplasmin and iron transferrin in patients with chronic lymphocytic leukaemia.
- Authors: Green JA, Pocklington T, Dawson AA, Foster M
- Issue date: 1980 Mar
- [EPR study of the blood of animals during an acute radiation lesion].
- Authors: Avakian MA, Sharygin VL, Pulatova MK
- Issue date: 1986 Nov-Dec