Measurement of oestradiol receptors by five institutions on common tissue samples.
dc.contributor.author | King, R J | |
dc.contributor.author | Barnes, Diana M | |
dc.contributor.author | Hawkins, R A | |
dc.contributor.author | Leake, R E | |
dc.contributor.author | Maynard, P V | |
dc.contributor.author | Roberts, M M | |
dc.date.accessioned | 2011-11-10T13:33:31Z | |
dc.date.available | 2011-11-10T13:33:31Z | |
dc.date.issued | 1978-09 | |
dc.identifier.citation | Measurement of oestradiol receptors by five institutions on common tissue samples. 1978, 38 (3):428-30 Br. J. Cancer | en |
dc.identifier.issn | 0007-0920 | |
dc.identifier.pmid | 708574 | |
dc.identifier.uri | http://hdl.handle.net/10541/189290 | |
dc.description.abstract | The soluble oestrogen-receptor content of common breast tumours has been measured by 5 different laboratories, each using their own assay procedure. Good agreement was achieved on whether a sample was positive or negative for oestrogen receptor. Qualitative differences between laboratories could be explained by differences in thiol-reagent content of assay medium and by the method of homogenization. Recommendations are made on some of the factors involved in the routine assay of receptors in breast tumours. | |
dc.language.iso | en | en |
dc.subject.mesh | Breast Neoplasms | |
dc.subject.mesh | Estradiol | |
dc.subject.mesh | Female | |
dc.subject.mesh | Great Britain | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Methods | |
dc.subject.mesh | Receptors, Estrogen | |
dc.subject.mesh | Sulfhydryl Compounds | |
dc.subject.mesh | Tissue Preservation | |
dc.title | Measurement of oestradiol receptors by five institutions on common tissue samples. | en |
dc.type | Article | en |
dc.contributor.department | Christie Hospital, Withington, Manchester, M20 4BX, UK | en |
dc.identifier.journal | British Journal of Cancer | en |
dc.identifier.pmcid | PMC2009740 | |
html.description.abstract | The soluble oestrogen-receptor content of common breast tumours has been measured by 5 different laboratories, each using their own assay procedure. Good agreement was achieved on whether a sample was positive or negative for oestrogen receptor. Qualitative differences between laboratories could be explained by differences in thiol-reagent content of assay medium and by the method of homogenization. Recommendations are made on some of the factors involved in the routine assay of receptors in breast tumours. |