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dc.contributor.authorHann, I M
dc.contributor.authorEvans, D I
dc.contributor.authorMarsden, Henry B
dc.contributor.authorMorris Jones, Patricia H
dc.contributor.authorPalmer, Michael K
dc.date.accessioned2011-11-08T13:12:30Z
dc.date.available2011-11-08T13:12:30Z
dc.date.issued1978-04
dc.identifier.citationBone marrow fibrosis in acute lymphoblastic leukaemia of childhood. 1978, 31 (4):313-5 J Clin Patholen
dc.identifier.issn0021-9746
dc.identifier.pmid273620
dc.identifier.doi10.1136/jcp.31.4.313
dc.identifier.urihttp://hdl.handle.net/10541/189090
dc.description.abstractA prospective study of bone marrow fibrosis was made in a group of 40 children with acute lymphoblastic leukaemia to see whether it affected the prognosis or course of the disease. Secondary myelofibrosis (SMF) was present at diagnosis in 57% of the cases. It was not statistically significantly related to the prognosis or course of the disease. Thus, although trephine biopsy occasionally provided useful information in different diagnosis and when aspiration was difficult, it provided little information of use for management.
dc.language.isoenen
dc.subject.meshBone Marrow
dc.subject.meshChild
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshLeukemia, Lymphoid
dc.subject.meshMale
dc.subject.meshPrimary Myelofibrosis
dc.subject.meshProspective Studies
dc.subject.meshRemission, Spontaneous
dc.titleBone marrow fibrosis in acute lymphoblastic leukaemia of childhood.en
dc.typeArticleen
dc.contributor.departmentChristie Hospital, Withington, Manchester, M20 4BX, UKen
dc.identifier.journalJournal of Clinical Pathologyen
html.description.abstractA prospective study of bone marrow fibrosis was made in a group of 40 children with acute lymphoblastic leukaemia to see whether it affected the prognosis or course of the disease. Secondary myelofibrosis (SMF) was present at diagnosis in 57% of the cases. It was not statistically significantly related to the prognosis or course of the disease. Thus, although trephine biopsy occasionally provided useful information in different diagnosis and when aspiration was difficult, it provided little information of use for management.


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