Show simple item record

dc.contributor.authorHendry, Jolyon H
dc.contributor.authorRosenberg, I
dc.contributor.authorGreene, D
dc.contributor.authorStewart, J
dc.date.accessioned2011-08-11T12:46:54Z
dc.date.available2011-08-11T12:46:54Z
dc.date.issued1977-08
dc.identifier.citationRe-irradiation of rat tails to necrosis at six months after treatment with a "tolerance" dose of x rays or neutrons. 1977, 50 (596):567-72 Br J Radiolen
dc.identifier.issn0007-1285
dc.identifier.pmid890231
dc.identifier.urihttp://hdl.handle.net/10541/139519
dc.description.abstractRat tails were re-irradiated to necrosis levels at about six months after various fractionated treatments with 290 kV X rays or 14 MeV neutrons. The X ray dose required to produce necrosis in half of a group of tails (ND50), which had been heavily X-irradiated six months before, was 91+/-4% of the ND50 for aged controls. After prior neutron-irradiation, however, this value was 87+/-4% (neutrons in second treatment) or 75+/-5% (X rays in second course). The "effective" oxygenation of mouse tails at this time after X-irradiation was similar to that of controls; thus these percentage dose values indicate the remarkable tolerance of this organized tissue to a second course of X-irradiation, and the presence of more residual injury in neutron-irradiated tissues.
dc.language.isoenen
dc.subject.meshAnimals
dc.subject.meshFemale
dc.subject.meshMice
dc.subject.meshNecrosis
dc.subject.meshNeutrons
dc.subject.meshRadiation Dosage
dc.subject.meshRadiation Injuries, Experimental
dc.subject.meshRadiation Tolerance
dc.subject.meshRats
dc.subject.meshTail
dc.subject.meshTime Factors
dc.subject.meshX-Rays
dc.titleRe-irradiation of rat tails to necrosis at six months after treatment with a "tolerance" dose of x rays or neutrons.en
dc.typeArticleen
dc.contributor.departmentPaterson Laboratories, Christie Hospital and Holt Radium Institute, Manchesteren
dc.identifier.journalThe British Journal of Radiologyen
html.description.abstractRat tails were re-irradiated to necrosis levels at about six months after various fractionated treatments with 290 kV X rays or 14 MeV neutrons. The X ray dose required to produce necrosis in half of a group of tails (ND50), which had been heavily X-irradiated six months before, was 91+/-4% of the ND50 for aged controls. After prior neutron-irradiation, however, this value was 87+/-4% (neutrons in second treatment) or 75+/-5% (X rays in second course). The "effective" oxygenation of mouse tails at this time after X-irradiation was similar to that of controls; thus these percentage dose values indicate the remarkable tolerance of this organized tissue to a second course of X-irradiation, and the presence of more residual injury in neutron-irradiated tissues.


This item appears in the following Collection(s)

Show simple item record