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    Re-irradiation of rat tails to necrosis at six months after treatment with a "tolerance" dose of x rays or neutrons.

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    Authors
    Hendry, Jolyon H
    Rosenberg, I
    Greene, D
    Stewart, J
    Affiliation
    Paterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester
    Issue Date
    1977-08
    
    Metadata
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    Abstract
    Rat tails were re-irradiated to necrosis levels at about six months after various fractionated treatments with 290 kV X rays or 14 MeV neutrons. The X ray dose required to produce necrosis in half of a group of tails (ND50), which had been heavily X-irradiated six months before, was 91+/-4% of the ND50 for aged controls. After prior neutron-irradiation, however, this value was 87+/-4% (neutrons in second treatment) or 75+/-5% (X rays in second course). The "effective" oxygenation of mouse tails at this time after X-irradiation was similar to that of controls; thus these percentage dose values indicate the remarkable tolerance of this organized tissue to a second course of X-irradiation, and the presence of more residual injury in neutron-irradiated tissues.
    Citation
    Re-irradiation of rat tails to necrosis at six months after treatment with a "tolerance" dose of x rays or neutrons. 1977, 50 (596):567-72 Br J Radiol
    Journal
    The British Journal of Radiology
    URI
    http://hdl.handle.net/10541/139519
    PubMed ID
    890231
    Type
    Article
    Language
    en
    ISSN
    0007-1285
    Collections
    All Paterson Institute for Cancer Research

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