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    Visualizing hormone actions in the brain.

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    Authors
    Brabant, Georg E
    Cain, John
    Jackson, Alan
    Kreitschmann-Andermahr, Ilonka
    Affiliation
    Department of Endocrinology, The Christie, Manchester Academic Health Science Centre, Wilmslow Road, Manchester M20 4BX, UK. georg.brabant@manchester.ac.uk
    Issue Date
    2011-05
    
    Metadata
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    Abstract
    Profound and multifaceted effects of hormones on the development, maturation and function of the CNS are well documented. Recent developments in magnetic resonance imagining (MRI) and positron emission tomography (PET) permit detailed in vivo studies of cerebral structure and function in humans. Techniques to measure subtle differences in cerebral structure, regional brain activation, changes in blood flow and other physiological biomarkers allow us to translate experimental evidence of hormone effects obtained from animal models to humans. Here we review the imaging techniques available to support studies of hormone effects on the CNS, emphasizing the recent developments of MRI. In summarizing the major current studies we discuss the potential of these techniques for an emerging new field in endocrinology.
    Citation
    Visualizing hormone actions in the brain. 2011, 22 (5):153-63 Trends Endocrinol Metab
    Journal
    Trends in Endocrinology and Metabolism
    URI
    http://hdl.handle.net/10541/136582
    DOI
    10.1016/j.tem.2011.01.004
    PubMed ID
    21497512
    Type
    Article
    Language
    en
    ISSN
    1879-3061
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.tem.2011.01.004
    Scopus Count
    Collections
    All Christie Publications
    Endocrinology

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