Acromegaly due to production of a growth hormone releasing factor by a bronchial carcinoid tumor.
Affiliation
Christie Hospital and Holt Radium Institute, ManchesterIssue Date
1979-01
Metadata
Show full item recordAbstract
We have studied growth hormone production in a patient with a bronchial carcinoid and acromegaly. The absence of growth hormone from the carcinoid tumour was demonstrated by extraction, cell culture and immunoperosidase techniques. Using a linked perfusion culture system, effluent from the bronchial carcinoid tumour culture stimulated a rapid release of growth hormone from a rat pituitary monolayer. This is the first time evidence of growth hormone releasing activity by a bronchial carcinoid has been demonstrated in a production.Citation
Acromegaly due to production of a growth hormone releasing factor by a bronchial carcinoid tumor. 1979, 10 (1):61-7 Clin EndocrinolJournal
Clinical EndocrinologyDOI
10.1111/j.1365-2265.1979.tb03034.xPubMed ID
219974Type
ArticleLanguage
enISSN
0300-0664ae974a485f413a2113503eed53cd6c53
10.1111/j.1365-2265.1979.tb03034.x
Scopus Count
Collections
Related articles
- Ectopic secretion of a growth hormone-releasing factor. Report of a case of acromegaly with bronchial carcinoid tumor.
- Authors: Scheithauer BW, Carpenter PC, Bloch B, Brazeau P
- Issue date: 1984 Apr
- A rare cause of acromegaly: ectopic production of growth hormone-releasing factor by a bronchial carcinoid tumor.
- Authors: Garcia-Luna PP, Leal-Cerro A, Montero C, Scheithauer BW, Campanario A, Dieguez C, Astorga R, Kovacs K
- Issue date: 1987 Jun
- Successful treatment by chemotherapy for acromegaly associated with ectopic growth hormone releasing hormone secretion from a carcinoid tumour.
- Authors: Harris PE, Bouloux PM, Wass JA, Besser GM
- Issue date: 1990 Mar
- Acromegaly due to ectopic growth hormone-releasing hormone secretion by a bronchial carcinoid tumour. Dynamic hormonal responses to various stimuli.
- Authors: Glikson M, Gil-Ad I, Galun E, Dresner R, Zilberman S, Halperin Y, Okon E, Laron Z, Rubinow A
- Issue date: 1991 Oct
- Resolution of acromegaly after removal of a bronchial carcinoid shown to secrete growth hormone releasing factor.
- Authors: Carroll DG, Delahunt JW, Teague CA, Cooke RR, Adams EF, Christofides ND, Bloom SR, Terenghi G, Polak JM
- Issue date: 1987 Feb