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    Tumour angiogenesis factor (TAF) and its neutralisation by a xenogeneic antiserum.

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    Authors
    Phillips, Paul
    Kumar, Shant
    Affiliation
    Christie Hospital and Holt Radium Institute, Manchester
    Issue Date
    1979-01-15
    
    Metadata
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    Abstract
    Tumour angiogenesis factor (TAF) has been extracted from a variety of animal and human tumours. Its ability to induce neovascularization in two bioassays, viz. rat air-sac and chick chorioallantoic membrane, is demonstrated. Similar extracts from normal tissues fail to induce angiogenesis. TAF extracts have been used to raise a xenogeneic antiserum, the specificity of which was investigated using classical immunological methods. Its ability to neutralize the biological activity of TAF using the two in vivo assays, was also demonstrated.
    Citation
    Tumour angiogenesis factor (TAF) and its neutralisation by a xenogeneic antiserum. 1979, 23 (1):82-8 Int J Cancer
    Journal
    International Journal of Cancer
    URI
    http://hdl.handle.net/10541/136554
    DOI
    10.1002/ijc.2910230115
    PubMed ID
    365782
    Type
    Article
    Language
    en
    ISSN
    0020-7136
    ae974a485f413a2113503eed53cd6c53
    10.1002/ijc.2910230115
    Scopus Count
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