A pulse radiolysis study of the complexing of furocoumarins with DNA and proteins.
| dc.contributor.author | Beaumont, P C | |
| dc.contributor.author | Land, Edward J | |
| dc.contributor.author | Navaratnam, S | |
| dc.contributor.author | Parsons, B J | |
| dc.contributor.author | Phillips, G O | |
| dc.date.accessioned | 2011-06-29T17:47:20Z | |
| dc.date.available | 2011-06-29T17:47:20Z | |
| dc.date.issued | 1980-06-27 | |
| dc.identifier.citation | A pulse radiolysis study of the complexing of furocoumarins with DNA and proteins. 1980, 608 (1):182-9 Biochim Biophys Acta | en |
| dc.identifier.issn | 0006-3002 | |
| dc.identifier.pmid | 7190027 | |
| dc.identifier.uri | http://hdl.handle.net/10541/134902 | |
| dc.description.abstract | The complexing of furocoumarins with DNA in aqueous solution has been investigated using the fast-reaction technique of pulse radiolysis. Association constants are given for 8-methoxypsoralen, psoralen, khellin, angelicin, 5,7-dimethoxycoumarin, 5-methoxypsoralen and 4'-aminomethyl-4,5',8-trimethylpsoralen. In addition, the complexing of some furocoumarins to the protein, bovine serum albumin, has also been studied. | |
| dc.language.iso | en | en |
| dc.subject.mesh | Animals | |
| dc.subject.mesh | Binding Sites | |
| dc.subject.mesh | Cattle | |
| dc.subject.mesh | DNA | |
| dc.subject.mesh | Kinetics | |
| dc.subject.mesh | Particle Accelerators | |
| dc.subject.mesh | Protein Binding | |
| dc.subject.mesh | Psoralens | |
| dc.subject.mesh | Serum Albumin, Bovine | |
| dc.subject.mesh | Structure-Activity Relationship | |
| dc.subject.mesh | Thymus Gland | |
| dc.title | A pulse radiolysis study of the complexing of furocoumarins with DNA and proteins. | en |
| dc.type | Article | en |
| dc.contributor.department | Paterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester, M20 9BX, England | en |
| dc.identifier.journal | Biochimica et Biophysica Acta | en |
| html.description.abstract | The complexing of furocoumarins with DNA in aqueous solution has been investigated using the fast-reaction technique of pulse radiolysis. Association constants are given for 8-methoxypsoralen, psoralen, khellin, angelicin, 5,7-dimethoxycoumarin, 5-methoxypsoralen and 4'-aminomethyl-4,5',8-trimethylpsoralen. In addition, the complexing of some furocoumarins to the protein, bovine serum albumin, has also been studied. |