Collagenase immunolocalization studies of cutaneous secondary melanomas.
Affiliation
University Department of Medicine, University Hospital of South ManchesterIssue Date
1980-08
Metadata
Show full item recordAbstract
Immunoreactive collagenase has been demonstrated in 5/14 specimens of cutaneous secondary melanomas. In contrast, very little enzyme was seen in 10 specimens of normal human skin. All specimens were fixed within minutes of excision. These findings support the hypothesis that collagenase facilitates connective-tissue breakdown which is associated with tumour invasiveness and metastatic spread.Citation
Collagenase immunolocalization studies of cutaneous secondary melanomas. 1980, 42 (2):260-5 Br J CancerJournal
British Journal of CancerPubMed ID
6252926Type
ArticleLanguage
enISSN
0007-0920Collections
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