Changes in proliferative activity as cells move along undulating basement membranes in stratified squamous epithelium.
| dc.contributor.author | Hume, W J | |
| dc.contributor.author | Potten, Christopher S | |
| dc.date.accessioned | 2011-06-29T17:22:41Z | |
| dc.date.available | 2011-06-29T17:22:41Z | |
| dc.date.issued | 1980-11 | |
| dc.identifier.citation | Changes in proliferative activity as cells move along undulating basement membranes in stratified squamous epithelium. 1980, 103 (5):499-504 Br J Dermatol | en |
| dc.identifier.issn | 0007-0963 | |
| dc.identifier.pmid | 7437316 | |
| dc.identifier.doi | 10.1111/j.1365-2133.1980.tb01664.x | |
| dc.identifier.uri | http://hdl.handle.net/10541/134891 | |
| dc.description.abstract | The filiform papillae of mouse tongue provide evidence for a flow of interphase basal cells along the basement membrane. This implies that they are aligned on that structure according to age. In addition there is a decrease in proliferative potential as the basal cells age. This is probably due at least in part to a fall in growth fraction. Such a method of basal cell replacement may exist in other stratified squamous epithelia characterized by undulating basement membranes. | |
| dc.language.iso | en | en |
| dc.subject.mesh | Animals | |
| dc.subject.mesh | Basement Membrane | |
| dc.subject.mesh | Cell Division | |
| dc.subject.mesh | Cell Movement | |
| dc.subject.mesh | Cell Survival | |
| dc.subject.mesh | Circadian Rhythm | |
| dc.subject.mesh | Epithelial Cells | |
| dc.subject.mesh | Female | |
| dc.subject.mesh | Interphase | |
| dc.subject.mesh | Male | |
| dc.subject.mesh | Mice | |
| dc.subject.mesh | Mice, Inbred DBA | |
| dc.subject.mesh | Mitotic Index | |
| dc.subject.mesh | Tongue | |
| dc.title | Changes in proliferative activity as cells move along undulating basement membranes in stratified squamous epithelium. | en |
| dc.type | Article | en |
| dc.contributor.department | Paterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester M20 9BX | en |
| dc.identifier.journal | British Journal of Dermatology | en |
| html.description.abstract | The filiform papillae of mouse tongue provide evidence for a flow of interphase basal cells along the basement membrane. This implies that they are aligned on that structure according to age. In addition there is a decrease in proliferative potential as the basal cells age. This is probably due at least in part to a fall in growth fraction. Such a method of basal cell replacement may exist in other stratified squamous epithelia characterized by undulating basement membranes. |