Changes in proliferative activity as cells move along undulating basement membranes in stratified squamous epithelium.
AffiliationPaterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester M20 9BX
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AbstractThe filiform papillae of mouse tongue provide evidence for a flow of interphase basal cells along the basement membrane. This implies that they are aligned on that structure according to age. In addition there is a decrease in proliferative potential as the basal cells age. This is probably due at least in part to a fall in growth fraction. Such a method of basal cell replacement may exist in other stratified squamous epithelia characterized by undulating basement membranes.
CitationChanges in proliferative activity as cells move along undulating basement membranes in stratified squamous epithelium. 1980, 103 (5):499-504 Br J Dermatol
JournalBritish Journal of Dermatology
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