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dc.contributor.authorNaha, P M
dc.date.accessioned2011-06-29T13:06:05Z
dc.date.available2011-06-29T13:06:05Z
dc.date.issued1980-09
dc.identifier.citationAn experimental model for selective inhibition of proliferating cells by chemotherapeutic agents. 1980, 4 (9):829-39 Cell Biol. Int. Rep.en
dc.identifier.issn0309-1651
dc.identifier.pmid6774818
dc.identifier.urihttp://hdl.handle.net/10541/134855
dc.description.abstractConditionally transformable cells of primate origin in which 'untransformed' and 'transformed' cells derived from the same source grow in culture, has been used as an experimental system for testing selective inhibition of proliferating cells by chemotherapeutic agents. The cytotoxic agents Adriamycin and Mitomycin C fail to recognise "tumour cells" in a heterogenous population and thus differ from the non-toxic and non-carcinogenic agent L-canavanine.
dc.language.isoenen
dc.subjectCanceren
dc.subject.meshAnimals
dc.subject.meshCanavanine
dc.subject.meshCell Division
dc.subject.meshCell Line
dc.subject.meshDoxorubicin
dc.subject.meshHaplorhini
dc.subject.meshKidney Neoplasms
dc.subject.meshMitomycins
dc.subject.meshModels, Biological
dc.subject.meshNeoplasms, Experimental
dc.titleAn experimental model for selective inhibition of proliferating cells by chemotherapeutic agents.en
dc.typeArticleen
dc.contributor.departmentPaterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester M20 9BX, U.Ken
dc.identifier.journalCell Biology International Reportsen
html.description.abstractConditionally transformable cells of primate origin in which 'untransformed' and 'transformed' cells derived from the same source grow in culture, has been used as an experimental system for testing selective inhibition of proliferating cells by chemotherapeutic agents. The cytotoxic agents Adriamycin and Mitomycin C fail to recognise "tumour cells" in a heterogenous population and thus differ from the non-toxic and non-carcinogenic agent L-canavanine.


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