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    The production of putative osteoclasts in tissue culture - ultrastructure, formation and behavior.

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    Authors
    Allen, Terence D
    Testa, Nydia G
    Suda, T
    Schor, Seth L
    Onions, D E
    Jarrett, O
    Boyde, A
    Issue Date
    1981
    
    Metadata
    Show full item record
    Abstract
    A system for culture of cat bone marrow produces multinucleate cells (50-100 nuclei) of large proportions (300 micrometer diameter). Scanning and transmission electron microscopy indicates that these cells (not virally induced syncytia) are true osteoclasts, which exhibit ultrastructural aspects of bone resorption (ruffled border and clear zones in TEM section, active spatulate cytoplasmic extensions in the SEM) even after 6 weeks culture on a plastic substratum. Observations have also been made regarding the formation of the multinucleate cells from apparently specific mononuclear precursors, and the behaviour of these cells on various substrata is also reported.
    Citation
    The production of putative osteoclasts in tissue culture - ultrastructure, formation and behavior. 1981 (Pt 3):347-54 Scan Electron Microsc
    Journal
    Scanning Electron Microscopy
    URI
    http://hdl.handle.net/10541/134853
    PubMed ID
    7330583
    Type
    Article
    Language
    en
    ISSN
    0586-5581
    Collections
    All Paterson Institute for Cancer Research

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